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Once in the cell, pemetrexed is converted to polyglutamate forms by the enzyme folylpolyglutamate synthetase

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What TB-500 contributes to KLOW: Cell migration — investigated effects on actin regulation and the physical movement of cells (fibroblasts, endothelial cells, immune cells) toward sites of repair or maintenance Connective tissue research relevance — TB-500 has substantial published research in tendon and ligament biology where cell migration is a recognized bottleneck