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If you notice that a stored peptide requires higher concentrations to achieve previously observed effects, degradation is likely occurring

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Likewise, spermidine-treated rice cultivars demonstrate reduced ROS and MDA levels, leading to improved shoot growth and overall plant development under high-temperature conditions ( Priming activates ROS-scavenging enzymes, heat shock proteins (HSPs), and molecular chaperones, enhancing abiotic stress tolerance in crops like pepper, maize, soybean, spinach, and wheat (Iqbal and Ashraf, 2007