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Known Side Effects acid reflux allergic reaction anxiety appetite suppression blood pressure elevation bruising circulation problems cold fingertips cold-like symptoms confusion constipation depression diarrhea difficulty breathing dizziness excessive sweating exhaustion extreme cortisol and adrenaline responses fatigue fibromyalgia hair loss heart palpitations heartburn high blood pressure hives hormonal side effects hyperhidrosis hypersensitivity/allergic reaction inflamed nerve pathways injection pain injection site brown discoloration injection site itching injection site rash injection site reactions injection site scarring irritable bowel syndrome-like symptoms itching until bleeding migraine after infusion migraine exacerbation muscle pain nasty reaction nausea neck inflammation non-stop migraine numbness in hands one-sided eye pain palpitations panic attack pulsatile tinnitus racing heart beat red fingertips redness reduced motivation restless legs runny nose scalp inflammation severe constipation severe itching in various parts of body severe reaction severe reaction lasting a year shaking sore throat tinea versicolor rash weight gain worsened pain worsening of migraines worsening of resting migraine Cautions ⚠ Not recommended during pregnancy ✓ Considered safe for long-term use Who Should Consider Aimovig (erenumab)