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This review will focus on FDA-approved and late-stage ADCs, their limitations including their toxicity and associated resistance mechanisms, as well as new emerging strategies to address these issues and attempt to widen their therapeutic window

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Uses FDA-Approved Uses Cyanocobalamin (Vitamin B12) injections are FDA-approved to treat vitamin B12 deficiency that may be caused by dietary limitations, pernicious anemia, pregnancy, and certain gastrointestinal disorders

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