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Nat Rev Endocrinol (2023) 19, 722–740

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Comprehensive safety telemetry concerning BPC-157 and mucosal administration formats like BPC-157 Nasal Spray requires multi-tier verification of nose-to-brain delivery efficiency and gastric mucosa bypass, with rigorous documentation tracking potential adverse outcomes such as mild nasal irritation, localized dryness, transient congestion, and variable bioavailability compared to subcutaneous routes