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Furthermore, reduced expression of melatonin receptor 1A (MT1) in astrocytes leads to increased pathological Ca 2+ influx, exacerbating oxidative stress and suppressing the NRF2/SLC7A11/GPX4 antioxidant axis, ultimately promoting neuronal ferroptosis (Zhang S

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[DOI] [PMC free article] [PubMed] [Google Scholar] 58.Varricchi G., Poto R