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The overall impression from available evidence is that DSIP appears reasonably well-tolerated with a low incidence of serious adverse effects in the populations and contexts studied, but significant gaps in safety knowledge remain, particularly regarding long-term use, use in specific populations (elderly, children, those with comorbidities), and comprehensive toxicology assessment meeting modern pharmaceutical standards

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It is one of the most complex regenerative events in the human body, requiring precise coordination between immune cells, stem cells, blood vessels, and nerve endings across weeks and months of continuous biological activity