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Notably, total nucleosome concentrations (absolute total CCFNs, regardless of histone modification) are only an indicator of cell damage, while CCFNs with specific nucleosome modifications can determine the cause of cell damage and possibly serve as useful markers for renal allograft rejection

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H ab is the resonance energy arising from electronic wave function mixing between the reactant and product electronic wave functions induced by the perturbation between sites, H ab = 〈Ψ p | Ĥ | Ψ r 〉 with Ψ r and Ψ r the reactant and product electronic wave functions

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