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Together with the notions mentioned earlier on iron’s role in supporting bacterial and viral infections, these insights suggest that pharmacological reduction of iron levels can help to dampen inflammatory and immune responses

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Binding activates adenylyl cyclase, raises intracellular cyclic AMP, and activates protein kinase A, which drives the steroidogenic cascade (StAR protein expression, CYP11A1 activity) leading to testosterone and progesterone synthesis