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and the acetylcysteine and Vitamin E group , where patients received standard psoriatic treatment in addition to acetylcysteine 600 mg effervescent granules (Acetylcistein ยฎ 600 mg Effervescent instant Granules, South Egypt Drug Industries company (SEDICO), 6th of October City, Egypt)) per day 30 min prior to breakfast for 8 weeks and one Vitamin E 1000 mg soft gelatin capsule per day (VITAMIN E ยฎ 1000 mg soft gelatin capsules, Safe for Pharmaceuticals (Safe Pharma) Pharco Pharmaceuticals, Alexandria, Egypt) [37]
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๐ง๐ต๐ฒ ๐ ๐ฎ๐ฟ๐ธ๐ฒ๐ ๐ฅ๐ฒ๐ฎ๐น๐ถ๐๐ ๐น Chronic disease is driving an unstoppable shift toward patient self-administration โ biologics that cannot be orally formulated must be injected, and patients expect devices that are intuitive, reliable and safe to use at home ๐น Fewer than 14% of drugs make it from Phase I to commercial market โ and usability gaps in combination products are increasingly cited in FDA Complete Response Letters, adding median delays of ~435 days before approval ๐น Pharma clients are now enquiring about PFS formats and autoinjector options before IND-enabling studies even begin โ device strategy is no longer a late-stage decision ๐น In an increasingly competitive landscape, the delivery system is a differentiator
